The series follows the professional and personal lives of six female comics in Los Angeles who are climbing their way to the top of the stand-up ladder. While the comediennes differ in their levels of experience, styles of comedy and ultimate career goals, they share the ambition and the passion needed to make it in the City of Dreams. From working multiple jobs, to clashing with parents expectations, to yet another bad date, the comics provide a fresh, witty perspective on experiences to which young millennial women can relate.